The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 78573-45-2, name is 3-(3-(Trifluoromethyl)phenyl)propan-1-ol. This compound has unique chemical properties. The synthetic route is as follows. 78573-45-2
Step 3: Preparation of Compound III (i.e., 3-(3-trifluoromethylphenyl)propanal) To a solution of 10 g (48 mmol) of Compound VII, 76.6 mg of TEMPO (2,2,6,6-tetramethyl-1-piperidinyloxy free radical) and 234 mg of potassium bromide in 70 mL methylene chloride was added 220 mL (pH=9.5) of sodium hypochlorite solution over 20 minutes at 10-15 C. with stirring. After five minutes of additional stirring, the organic layer was separated. The aqueous layer was extracted twice with 40 mL of methylene chloride, and the collected organic layers were dried and evaporated to yield 10 g of crude Compound III as a yellowish liquid. Yield: 100%; purity (determined by GC): 90.3%, contains 8.25% of Compound NMR data (200 MHz, CDCl3, ppm): 2.81 (t, 2H), 3.00 (t, 21-1), 7.37-7.46 (m, 4H), 9.80 (s, 1H).
Statistics shows that 78573-45-2 is playing an increasingly important role. we look forward to future research findings about 3-(3-(Trifluoromethyl)phenyl)propan-1-ol.
Reference:
Patent; Medichem, S.A.; US2010/267988; (2010); A1;,
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