124-76-5, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 124-76-5, name is Isoborneol. This compound has unique chemical properties. The synthetic route is as follows.
Example 5 Preparation of 1-[((1S)-endo)-(-)-bornyloxy]-5-(2-propenyl)-2-oxabicyclo[3.3.0]octane and separation of diastereomers (18a, 18b) 22.8 parts of ((1S)-endo)-(-)-borneol (10) was added to 35 ml of an anhydrous toluene solution containing 30 parts of 1-methoxy-5-(2-propenyl)-2-oxabicyclo[3.3.0]octane (16) and 30 parts of molecular-sieve 5A at room temperature. The mixture was stirred for 10 hours at 110C. In this instance, 600 parts of molecular-sieve (MS-4A) that can adsorb methanol was filled in the reflux tube to adsorb the methanol generated in the reflux tube. The reaction solution was filtrated. The filtrate was concentrated under reduced pressure to obtain 52 parts of a residue. The resulting residue was purified by silica gel column chromatography (n-hexane: diethyl ether = 40: 1) to obtain the target isomer mixture. Furthermore, the resulting isomer mixture was separated into individual diastereomers represented by (18a) and (18b) (Isomer 3 and Isomer 4) by silica gel column chromatography (n-hexane: diisopropyl ether = 1: 40). Isomer 3 (diastereomer having a larger Rf) and Isomer 4 (diastereomer having a smaller Rf) were obtained respectively in an amount of 17.1 parts (yield: 38%) and 18.9 parts (yield: 42%). The properties of the diastereomers represented by (18a and 18b) are shown as follows.
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 124-76-5, Isoborneol.
Reference:
Patent; Zeon Corporation; EP1535917; (2005); A1;,
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