A common compound: 6338-55-2, name is 2-(2-(2-Aminoethoxy)ethoxy)ethanol,molecular formula is C6H15NO3, it can change the direction of chemical reaction, and react with certain compounds to generate new functional products. A new synthetic method of this compound is introduced below., 6338-55-2
General procedure: The desired aminoalcohol (17 mmol, 2-(2-aminoethoxy)ethanol or 2-[2-(2-aminoethoxy)ethoxy]ethanol) was dissolved in CH3OH (10 mL) and TEA (5.45 mL, 39.2 mmol) was added. To this solution, stirred at room temperature, was added dropwise a solution of benzyloxycarbonyl chloride (ZCl, 3.2 g, 18.77 mmol) in CH3OH (5 mL). After the addition was complete the reaction mixture was stirred at room temperature for 20 h, protected from moisture with a CaCl2 drying tube. The solvent was then evaporated and the crude was dissolved in CH2Cl2 (150 mL) and washed first with a 5% aqueous solution of KHSO4 (2 ¡Á 50 mL) and then with water (2 ¡Á 50 mL). The evaporation of the dried solvent (Na2SO4) afforded the product as a clear oil pure enough to be used in the following steps.
With the rapid development of chemical substances, we look forward to future research findings about 6338-55-2.
Reference:
Article; Sissi, Claudia; Dovigo, Luca; Greco, Maria Laura; Ciancetta, Antonella; Moro, Stefano; Trzci?ski, Jakub W.; Mancin, Fabrizio; Rossi, Paola; Spalluto, Giampiero; Tecilla, Paolo; Tetrahedron; vol. 73; 21; (2017); p. 3014 – 3024;,
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