702-82-9, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 702-82-9, name is 3-Aminoadamantan-1-ol, molecular formula is C10H17NO, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
General procedure: A mixture of 0.136 or 0.272 g (1 or 2 mmol) of 1-oxa-3,6-dithiacycloheptane (1) [3] in 5 mL of chloroform and 0.018 g (0.05 mmol) of SmCl3 ¡¤ 6 H2O was stirred for 30 min at room temperature under argon, and a solution of 1 mmol of the corresponding amine in 5 mL of ethanol was added dropwise. The mixture was stirred for 3 h at room temperature, treated with 2 mL of water, stirred for 30 min more, and extracted with chloroform (20 mL). The extract was evaporated, and the product (compound 2-17) was isolated from the residue by column chromatography on silica gel.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 702-82-9, 3-Aminoadamantan-1-ol, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Rakhimova; Ismagilov; Khalilov; Zainullin; Ibragimov; Dzhemilev; Russian Journal of Organic Chemistry; vol. 51; 7; (2015); p. 951 – 956; Zh. Org. Khim.; vol. 51; 7; (2015); p. 971 – 976,6;,
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