With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.39590-81-3, name is 1,1-Bis(Hydroxymethyl)cyclopropane, molecular formula is C5H10O2, molecular weight is 102.13, as common compound, the synthetic route is as follows.39590-81-3
5 g of cyclopropane-1,1-diyldimethanol are solubilized in 31 mL of pyridine. Cooling is performed down to 0-5 C., and then 10.3 mL of mesyl chloride are added dropwise, stirring is performed for 2 h. Add 40.46 mL of H2O+12.24 mL of concentrated HCl in order to precipitate the compound. The precipitate is filtered and dried in the oven. 10 g (yield=80%) of cyclopropane-1,1-diylbis(methylene)dimethanesulfonate are obtained as a white powder:
Statistics shows that 39590-81-3 is playing an increasingly important role. we look forward to future research findings about 1,1-Bis(Hydroxymethyl)cyclopropane.
Reference:
Patent; SANOFI; Arigon, Jerome; Brollo, Maurice; Clement, Jacques; Combet, Romain; Durand, Florence; El Ahmad, Youssef; Labrosse, Jean-Robert; Letallec, Jean-Philippe; Ronan, Baptiste; US2013/289031; (2013); A1;,
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