440-60-8, In the chemical reaction process,reaction time,type of solvent,can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.An updated downstream synthesis route of 440-60-8 as follows.
In a 10 mL round bottom flask, 0.99 g of pentafluorobenzyl alcohol and 2 g of diethylene glycol dimethyl ether were sequentially added.The resulting mixture was subjected to ultrasonic irradiation at 40 kHz/30 W/70 C for 30 minutes in an ultrasonic reaction apparatus. The diethylene glycol dimethyl ether was removed under reduced pressure, and recrystallized to obtain 0.89 g of pentafluorobenzoic acid in a yield of 95%.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,440-60-8, its application will become more common.
Reference:
Patent; Central South University; Xiao Fang; Xiao Yuanyuan; Zeng Ming; Li Na; Yin Lirong; (15 pag.)CN108467342; (2018); A;,
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