78573-45-2, Adding a certain compound to certain chemical reactions, such as: 78573-45-2, 3-(3-(Trifluoromethyl)phenyl)propan-1-ol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 78573-45-2, blongs to alcohols-buliding-blocks compound.
Example 4 Preparation of methanesulfonic acid 3-(3-trifluoromethyl-phenyl)-propyl ester To a stirred solution of 3-(3-trifluoromethyl-phenyl)-propan-1-ol (250 g, 1.224 mol) and triethylamine (148.52 g, 1.47 mol) in dichloromethane (1.25 L), methanesulfonyl chloride (161.32 g, 1.41 mol) was added at 25 C. to 40 C. and reaction mixture was stirred for 2-3 hours at 40 C. Thereafter, reaction mixture was washed with demineralized water (500 ml*3) and dried over anhydrous sodium sulfate. The dichloromethane was distilled off to give 335 g of title compound having purity 91.58% by HPLC.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,78573-45-2, its application will become more common.
Reference:
Patent; IND-SWIFT LABORATORIES LIMITED; US2011/172455; (2011); A1;,
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