Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 112-70-9, name is 1-Tridecanol. A new synthetic method of this compound is introduced below., 112-70-9
General procedure: To a soln. of peracetyl beta-D-O-galactopyranoside 1 (1 equiv.) and the fatty alcohol (2-8, 2 equiv.) in dry MeCN (10 mL), was added BF3*Et2O (1 equiv.). This mixture was transferred into the microwave oven with rigorous stirring for 12 min at 120 C (ramp time: 10 min). Solvent was removed in vacuum, and the resulting residue was diluted with EtOAC and washed successively with sat. NaHCO3 and brine. The combined organic layer was dried over NaSO4, filtered, concentrated in vacuum to give a crude mixture residue which was separated by column chromatography.
At the same time, in my other blogs, there are other synthetic methods of this type of compound,112-70-9, 1-Tridecanol, and friends who are interested can also refer to it.
Reference:
Article; Song, Shao-Xing; Wu, Ming-Li; He, Xiao-Peng; Zhou, Yu-Bo; Sheng, Li; Li, Jia; Chen, Guo-Rong; Bioorganic and Medicinal Chemistry Letters; vol. 22; 5; (2012); p. 2030 – 2032;,
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